CROSPOVIDONE

CAS No. 25249-54-1 Chemical Information
English Name: Crospovidone
Synonyms: Cross-linked Povidone, Polyplasdone XL, PVPP 
Basic Parameters
Molecular Formula: (C₆H₉NO)n
Average Molecular Weight: Polymer (Variable)
Molecular Structure: 

Additional Information: Crospovidone (Cross-linked Povidone, PVPP) is a high-purity pharmacopoeia-grade water-insoluble polymer auxiliary material compliant with USP, EP and Chinese Pharmacopoeia standards. It features excellent capillary activity and strong water absorption and swelling properties, with no solubility in water, organic solvents and acidic/alkaline solutions. As a super disintegrant for oral solid preparations, it can rapidly absorb water and swell to break tablet structure, effectively improving tablet disintegration speed and drug dissolution rate. It also has excellent adsorption performance, capable of adsorbing tannins and polyphenolic impurities. Widely used in pharmaceutical tablets, capsules, granules and high-standard health care product formulations, it is the mainstream high-efficiency disintegrating agent and purification auxiliary material in the pharmaceutical industry.